How to: map protein sequence onto chromosomal coordinates using BioPerl

My coding challenge this week: given a protein sequence and its exons, how do you map single amino acid residues to a location on a DNA sequence? It’s trickier than you might think. Read on for my latest BioPerl how-to.

Best wishes to Jonathan Eisen

Just wanted to add my voice to the many congratulating Jonathan Eisen: biologist, blogger, Open Access advocate and all-round top bloke on his appointment to PLoS Biology Academic Editor in Chief. You can read his editorial to learn more about his motivation and plans for the journal.

Jonathan, you realise that you’re now the figurehead for the revolution, don’t you